Preparation of poly(methyl methacrylate) microcapsules by in situ polymerization on the surface of calcium carbonate particles

Katsuhiko Sato, Tatsuya Nakajima, Jun Ichi Anzai

Research output: Contribution to journalArticlepeer-review

9 Citations (Scopus)

Abstract

Poly(methyl methacrylate) (PMMA) microcapsules were prepared by the in situ polymerization of methyl methacrylate (MMA) and N,N'-methylenebisacrylamide on the surface of calcium carbonate (CaCO3) particles, followed by the dissolution of the CaCO3 core in ethylenediaminetetraacetic acid solution. The microcapsules were characterized using fluorescence microscopy, atomic force microscopy, scanning electron microscopy, and Fourier transform infrared spectroscopy. The average sizes of the CaCO3 particles and PMMA capsules were 3.8±0.6 and 4.0±0.6μm, respectively. A copolymer consisting of MMA and rhodamine B-bearing MMA was also used to prepare microcapsules for fluorescent microscopy observations. Fluorescein isothiocyanate-labeled bovine serum albumin was enclosed in the PMMA microcapsules and its release properties were studied.

Original languageEnglish
Pages (from-to)123-126
Number of pages4
JournalJournal of Colloid And Interface Science
Volume387
Issue number1
DOIs
Publication statusPublished - 2012 Dec 1

Keywords

  • Calcium carbonate particle
  • Poly(methyl methacrylate)
  • Polyelectrolyte microcapsule

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry

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