Preparation of molecular dispersed polymer blend composed of polyethylene and poly(vinyl acetate) by in situ polymerization of vinyl acetate using supercritical carbon dioxide

Toru Hoshi, Takashi Sawaguchi, Tomohiro Konno, Madoka Takai, Kazuhiko Ishihara

Research output: Contribution to journalArticlepeer-review

26 Citations (Scopus)

Abstract

A novel polymer blend comprising polyethylene (PE) and poly(vinyl acetate) (PVAc) with a biocompatible surface was developed for fabricating medical devices. This blend was obtained by a new synthetic method using supercritical carbon dioxide fluid. Further, the acetyl group on the surface of this blend was converted to the hydroxyl group following the phosphorylcholine (PC) group. Surface analysis of the blend with attenuated total reflection Fourier-transform infrared spectroscopy, X-ray photoelectron spectroscopy and dynamic contact angle measurement revealed that the PC groups were located on the surface. Biocompatibility was evaluated by the adsorption of the bovine serum albumin and bovine plasma fibrinogen on the sheet surface. The hydrophilicity of the blend depended on the surface chemical structure introduced by surface reactions. Plasma protein adsorption decreased with the surface hydrophilicity. The PC groups were highly effective in reducing protein adsorption. We conclude that our process is a promising procedure for synthesizing new polymer materials including biomaterials.

Original languageEnglish
Pages (from-to)1573-1580
Number of pages8
JournalPolymer
Volume48
Issue number6
DOIs
Publication statusPublished - 2007 Mar 8
Externally publishedYes

Keywords

  • Phosphorylcholine
  • Polyethylene
  • Supercritical carbon dioxide

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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