Preparation of bioactive inorganic-organic hybrids by hot water treatment

Masakazu Kawashita, M. Kamitakahara, N. Miyata, T. Kokubo, T. Nakamura

Research output: Contribution to journalConference article


Bioactive inorganic-organic hybrids with high flexibility are useful for a new kind of bone-repairing materials. In the present study, preparation of bioactive poly(dimethylsiloxane) (PDMS) or poly(tetramethylene oxide) (PTMO)-TiO2 hybrids was attempted by sol-gel method and subsequent hot water treatment. Both of the hybrids showed an apatite-forming ability in a simulated body fluid with ion concentrations nearly equal to those of human blood plasma. It is considered that apatite formation is induced by anatase precipitated by the hot water treatment. The resultant hybrids showed high deformability. It can be concluded that bioactive inorganic-organic hybrids with high flexibility can be obtained by the present method.

Original languageEnglish
Pages (from-to)221-226
Number of pages6
JournalCeramic Engineering and Science Proceedings
Issue number3
Publication statusPublished - 2003 Dec 9
EventCeramic Engineering And Science Proceedings: 27th International Cocoa Beach Conference on Advanced Ceramics and Composites:A - Cocoa Beach, FL, United States
Duration: 2003 Jan 262003 Jan 31

ASJC Scopus subject areas

  • Ceramics and Composites
  • Materials Chemistry

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