Preparation of 1,2-dihydroisoquinolines by a three-component reaction under catalyst-free conditions

Kentaro Iso, S. Salprima Yudha, Naoki Asao

    Research output: Contribution to journalArticle

    7 Citations (Scopus)

    Abstract

    A variety of 1,2-dihydroisoquinoline derivatives have been efficiently prepared by a three-component reaction using ortho-alkynylbenzaldehydes, primary amines, and pronucleophiles under mild catalyst-free conditions.

    Original languageEnglish
    Pages (from-to)820-822
    Number of pages3
    JournalSynthesis
    Issue number5
    DOIs
    Publication statusPublished - 2008 Mar 3

    Keywords

    • 1,2-dihydroisoquinoline
    • Catalyst-free conditions
    • Direct addition
    • Multicomponent reaction
    • Pronucleophile

    ASJC Scopus subject areas

    • Organic Chemistry

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