Preparation and compressive strength of α-tricalcium phosphate/gelatin gel composite cement

Y. Fujishiro, K. Takahashi, T. Sato

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    59 Citations (Scopus)

    Abstract

    A novel α-tricalcium phosphate (TCP) and gelatin gel composite cement was prepared, and the effects of gelatin content, liquid/powder ratio, setting time, and additives (rod-like hydroxyapatite and CaTiO3 particles) on the microstructure and compressive strength of the setting product were investigated. Addition of gelatin gel to α-TCP cement resulted in the formation of a porous solid possessing pores of 20-100 μm in diameter whose pore diameter increased with increasing gelatin gel content. The compressive strength of α-TCP cement after I week increased from 9.0 to 14.1 MPa with increasing gelatin gel content up to 5 wt % and thereafter decreased. The compressive strength of the cement containing 5 wt % gelatin gel increased with time up to 35 MPa after 1 month whereas without gelatin gel it was ∼20 MPa. Dispersion of 5 wt % of rod-like hydroxyapatite and CaTiO3 powders with α-TCP cement containing 5 wt % gelatin gel increased the compressive strength after 1 week from 14.1 to 31.3 and 34.8 MPa, respectively.

    Original languageEnglish
    Pages (from-to)525-530
    Number of pages6
    JournalJournal of Biomedical Materials Research
    Volume54
    Issue number4
    DOIs
    Publication statusPublished - 2001 Mar 15

    Keywords

    • CaTiO particles
    • Compressive strength
    • Gelatin
    • Hydroxyapatite particles
    • Tricalcium phosphate cement

    ASJC Scopus subject areas

    • Biomaterials
    • Biomedical Engineering

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