Prefrontal cortical cells projecting to the supplementary eye field and presupplementary motor area in the monkey

Yan Wang, Masaki Isoda, Yoshiya Matsuzaka, Keisetsu Shima, Jun Tanji

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57 Citations (Scopus)

Abstract

We examined the location and spatial distribution of prefrontal cortical (PF) cells projecting to the supplementary eye field (SEF) and presupplementary motor area (pre-SMA) using a double retrograde-labeling technique in monkeys (Macaca fuscata). The SEF and pre-SMA were physiologically identified based on the findings of intracortical microstimulation and single cell recordings. Two fluorescent tracers, diamidino yellow and fast blue, were injected into the SEF and pre-SMA of each monkey. Retrogradely labeled cells in the PF were plotted with an automated plotting system. The cells projecting to the SEF and pre-SMA were mainly distributed in the upper and lower banks of the principal sulcus (area 46), with little overlap. Cells projecting to the SEF, but not to the pre-SMA, were observed in areas 8a, 8b, 9, 12, and 45. These findings suggest that the SEF and pre-SMA receive different sets of information from the PF cells.

Original languageEnglish
Pages (from-to)1-7
Number of pages7
JournalNeuroscience Research
Volume53
Issue number1
DOIs
Publication statusPublished - 2005 Sep

Keywords

  • Prefrontal cortex
  • Presupplementary motor area
  • Primate
  • Retrograde labeling
  • Supplementary eye field

ASJC Scopus subject areas

  • Neuroscience(all)

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