Prediction of thermal coagulation from the instantaneous strain distribution induced by high-intensity focused ultrasound

Ryosuke Iwasaki, Ryo Takagi, Kentaro Tomiyasu, Shin Yoshizawa, Shin Ichiro Umemura

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

The targeting of the ultrasound beam and the prediction of thermal lesion formation in advance are the requirements for monitoring high-intensity focused ultrasound (HIFU) treatment with safety and reproducibility. To visualize the HIFU focal zone, we utilized an acoustic radiation force impulse (ARFI) imaging-based method. After inducing displacements inside tissues with pulsed HIFU called the push pulse exposure, the distribution of axial displacements started expanding and moving. To acquire RF data immediately after and during the HIFU push pulse exposure to improve prediction accuracy, we attempted methods using extrapolation estimation and applying HIFU noise elimination. The distributions going back in the time domain from the end of push pulse exposure are in good agreement with tissue coagulation at the center. The results suggest that the proposed focal zone visualization employing pulsed HIFU entailing the high-speed ARFI imaging method is useful for the prediction of thermal coagulation in advance.

Original languageEnglish
Article number07JF23
JournalJapanese journal of applied physics
Volume56
Issue number7
DOIs
Publication statusPublished - 2017 Jul

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

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