Prediction of mortality by ambulatory blood pressure monitoring versus screening blood pressure measurements: A pilot study in Ohasama

Takayoshi Ohkubo, Yutaka Imai, Ichiro Tsuji, Kenichi Nagai, Noriko Watanabe, Naoyoshi Minami, Osamu Itoh, Takehiko Bando, Mariko Sakuma, Akira Fukao, Hiroshi Satoh, Shigeru Hisamichi, Keishi Abe

Research output: Contribution to journalArticlepeer-review

232 Citations (Scopus)

Abstract

Objective. To compare the prediction of mortality by ambulatory blood pressure monitoring and screening blood pressure measurements in a general population. Design. A prospective cohort study. Patients and methods. We obtained blood pressure data for 1542 subjects (565 men and 977 women) aged ≤ 40 years who were followed up for up to 8.1 years (mean 5.1 years). Subjects were subdivided into five groups according to their ambulatory and screening blood pressure levels. The prognostic significance of blood pressure for mortality was examined by the Cox proportional hazards regression model. Results. The association between blood pressure level and mortality was more distinctive for the ambulatory blood pressure than it was for the screening blood pressure. The risk of cardiovascular mortality increased significantly for the highest quintiles of 24 h ambulatory blood pressure, whereas there was no significant association between the screening blood pressure and the cardiovascular mortality. When both 24 h and screening blood pressure values were included in the Cox model, only the systolic ambulatory blood pressure was related significantly to the increased risk of cardiovascular mortality. Conclusions. The ambulatory blood pressure had a stronger predictive power for mortality than did the screening blood pressure. This appears to have been the first study of the prognostic significance of ambulatory blood pressure monitoring versus screening blood pressure measurements in a general population.

Original languageEnglish
Pages (from-to)357-364
Number of pages8
JournalJournal of hypertension
Volume15
Issue number4
DOIs
Publication statusPublished - 1997

Keywords

  • Ambulatory blood pressure
  • Mortality
  • Population-based subjects
  • Prospective study
  • Screening blood pressure

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology
  • Cardiology and Cardiovascular Medicine

Fingerprint

Dive into the research topics of 'Prediction of mortality by ambulatory blood pressure monitoring versus screening blood pressure measurements: A pilot study in Ohasama'. Together they form a unique fingerprint.

Cite this