Practical synthesis of chiral ligands for catalytic enantioselective cyanosilylation of ketones and ketoimines

Nobuki Kato, Daisuke Tomita, Keisuke Maki, Motomu Kanai, Masakatsu Shibasaki

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)

Abstract

A practical synthesis of chiral ligands that are useful for catalytic enantioselective cyanosilylation of ketones and ketoimines is described. Compared with the previous synthetic route, the number of total steps is decreased and the total yield is greatly improved. Furthermore, both (+)- and (-)-ligands are readily available by this new synthetic route.

Original languageEnglish
Pages (from-to)6128-6130
Number of pages3
JournalJournal of Organic Chemistry
Volume69
Issue number18
DOIs
Publication statusPublished - 2004 Sep 3
Externally publishedYes

ASJC Scopus subject areas

  • Organic Chemistry

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