Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture

Toshikazu Samura; Yasuomi D. Sato; Yuji Ikegaya; Hatsuo Hayashi

doi:10.1007/978-3-642-24955-6_45

Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture

Toshikazu Samura, Yasuomi D. Sato, Yuji Ikegaya, Hatsuo Hayashi

INF - System Information Sciences

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

We study on computer simulations to infer a network structure of the hippocampal CA3 culture slice, which is not yet found even in physiological experiments. In order to find the network structure, we have to understand dynamical mechanisms of how to establish two power law distributions of spontaneous activities observed in the CA3 cultured slice. The first power law is the probabilistic distribution of firing frequency in a neuron. The second is of synchrony size that means a rate of co-active neurons within a time bin. In this work, we show that the power law observations significantly rely on the two network mechanisms: (1) high-frequency firing of interneurons by feedback from pyramidal cells, (2) log-normal distribution of synaptic weights.

Original language	English
Title of host publication	Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings
Pages	370-379
Number of pages	10
Edition	PART 1
DOIs	https://doi.org/10.1007/978-3-642-24955-6_45
Publication status	Published - 2011
Event	18th International Conference on Neural Information Processing, ICONIP 2011 - Shanghai, China Duration: 2011 Nov 13 → 2011 Nov 17

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Number	PART 1
Volume	7062 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	18th International Conference on Neural Information Processing, ICONIP 2011
Country	China
City	Shanghai
Period	11/11/13 → 11/11/17

Keywords

CA3
Hippocampus
Inhibitory interneurons
Log-normal distribution
Power-law distribution
Spontaneous activity

ASJC Scopus subject areas

Theoretical Computer Science
Computer Science(all)

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Samura, T., Sato, Y. D., Ikegaya, Y., & Hayashi, H. (2011). Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture. In Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings (PART 1 ed., pp. 370-379). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 7062 LNCS, No. PART 1). https://doi.org/10.1007/978-3-642-24955-6_45

Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture. / Samura, Toshikazu; Sato, Yasuomi D.; Ikegaya, Yuji; Hayashi, Hatsuo.

Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings. PART 1. ed. 2011. p. 370-379 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 7062 LNCS, No. PART 1).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Samura, T, Sato, YD, Ikegaya, Y & Hayashi, H 2011, Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture. in Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings. PART 1 edn, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 1, vol. 7062 LNCS, pp. 370-379, 18th International Conference on Neural Information Processing, ICONIP 2011, Shanghai, China, 11/11/13. https://doi.org/10.1007/978-3-642-24955-6_45

Samura T, Sato YD, Ikegaya Y, Hayashi H. Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture. In Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings. PART 1 ed. 2011. p. 370-379. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 1). https://doi.org/10.1007/978-3-642-24955-6_45

Samura, Toshikazu ; Sato, Yasuomi D. ; Ikegaya, Yuji ; Hayashi, Hatsuo. / Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture. Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings. PART 1. ed. 2011. pp. 370-379 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 1).

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