TY - GEN
T1 - Power laws for spontaneous neuronal activity in hippocampal CA3 slice culture
AU - Samura, Toshikazu
AU - Sato, Yasuomi D.
AU - Ikegaya, Yuji
AU - Hayashi, Hatsuo
PY - 2011
Y1 - 2011
N2 - We study on computer simulations to infer a network structure of the hippocampal CA3 culture slice, which is not yet found even in physiological experiments. In order to find the network structure, we have to understand dynamical mechanisms of how to establish two power law distributions of spontaneous activities observed in the CA3 cultured slice. The first power law is the probabilistic distribution of firing frequency in a neuron. The second is of synchrony size that means a rate of co-active neurons within a time bin. In this work, we show that the power law observations significantly rely on the two network mechanisms: (1) high-frequency firing of interneurons by feedback from pyramidal cells, (2) log-normal distribution of synaptic weights.
AB - We study on computer simulations to infer a network structure of the hippocampal CA3 culture slice, which is not yet found even in physiological experiments. In order to find the network structure, we have to understand dynamical mechanisms of how to establish two power law distributions of spontaneous activities observed in the CA3 cultured slice. The first power law is the probabilistic distribution of firing frequency in a neuron. The second is of synchrony size that means a rate of co-active neurons within a time bin. In this work, we show that the power law observations significantly rely on the two network mechanisms: (1) high-frequency firing of interneurons by feedback from pyramidal cells, (2) log-normal distribution of synaptic weights.
KW - CA3
KW - Hippocampus
KW - Inhibitory interneurons
KW - Log-normal distribution
KW - Power-law distribution
KW - Spontaneous activity
UR - http://www.scopus.com/inward/record.url?scp=81855172125&partnerID=8YFLogxK
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U2 - 10.1007/978-3-642-24955-6_45
DO - 10.1007/978-3-642-24955-6_45
M3 - Conference contribution
AN - SCOPUS:81855172125
SN - 9783642249549
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 370
EP - 379
BT - Neural Information Processing - 18th International Conference, ICONIP 2011, Proceedings
T2 - 18th International Conference on Neural Information Processing, ICONIP 2011
Y2 - 13 November 2011 through 17 November 2011
ER -