Abstract
We determined a number of miRNAs exist in rats after death using comprehensive microarray analysis with 350 rat miRNAs probes. Our analysis revealed that 237 miRNAs (67.7%) were under the threshold level and 105 (30%) were expressed until 48. h after death. Some miRNAs showed the unstable levels of expression at postmortem. Further investigations using quantitative PCR analysis and animal experiments are required before forensic application of this knowledge, such as estimation of time of death or quantification of stress.
Original language | English |
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Pages (from-to) | e210-e211 |
Journal | Forensic Science International: Genetics Supplement Series |
Volume | 3 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2011 Dec |
Keywords
- MicroRNA (miRNA)
- Microarray
- Postmortem
- Rat
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Genetics