Postcentral gyrus resection of opercular gliomas is a risk factor for motor deficits caused by damaging the radiologically invisible arteries supplying the descending motor pathway

Ichiyo Shibahara, Sumito Sato, Takuichiro Hide, Ryuta Saito, Masayuki Kanamori, Yukihiko Sonoda, Teiji Tominaga, Toshihiro Kumabe

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Postoperative motor deficits are among the worst morbidities of glioma surgery. We aim to investigate factors associated with postoperative motor deficits in patients with frontoparietal opercular gliomas. Methods: Thirty-four patients with frontoparietal opercular gliomas were retrospectively investigated. We examined the postoperative ischemic changes and locations obtained from MRI. Results: Twenty-one patients (62%) presented postoperative ischemic changes. Postoperative MRI was featured with ischemic changes, all located at the subcortical area of the resection cavity. Six patients had postoperative motor deficits, whereas 28 patients did not. Compared to those without motor deficits, those with motor deficits were associated with old age, pre- and postcentral gyri resection, and postcentral gyrus resection (P = 0.023, 0,024, and 0.0060, respectively). A merged image of the resected cavity and T1-weighted brain atlas of the Montreal Neurological Institute showed that a critical area for postoperative motor deficits is the origin of the long insular arteries (LIAs) and the postcentral gyrus. Detail anatomical architecture created by the Human Connectome Project database and T2-weighted images showed that the subcortical area of the operculum of the postcentral gyrus is where the medullary arteries supply, and the motor pathways originated from the precentral gyrus run. Conclusions: We verified that the origin of the LIAs could damage the descending motor pathways during the resection of frontoparietal opercular gliomas. Also, we identified that motor pathways run the subcortical area of the operculum of the postcentral gyrus, indicating that the postcentral gyrus is an unrecognized area of damaging the descending motor pathways.

Original languageEnglish
Pages (from-to)1269-1278
Number of pages10
JournalActa neurochirurgica
Volume163
Issue number5
DOIs
Publication statusPublished - 2021 May
Externally publishedYes

Keywords

  • Descending motor pathway
  • Glioma
  • Long insular artery
  • Medullary artery
  • Motor deficits
  • Operculum

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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