Positive expression of the immunoglobulin superfamily protein IZUMO on human sperm of severely infertile male patients

Shinichi Hayasaka, Yukihiro Terada, Naokazu Inoue, Masaru Okabe, Nobuo Yaegashi, Kunihiro Okamura

Research output: Contribution to journalArticlepeer-review

21 Citations (Scopus)

Abstract

Recently, the immunoglobulin superfamily protein IZUMO on the sperm surface was identified as being essential for sperm-egg fusion. Although we examined the expression of IZUMO on sperm of 13 male infertile patients with severe oligozoospermia and/or athenozoospermia and 12 infertile patients with fertilization failure in previous conventional IVF to determine whether it is varied in infertility patients, we could not identify any patients with IZUMO negative by immunocytochemistry.

Original languageEnglish
Pages (from-to)214-216
Number of pages3
JournalFertility and sterility
Volume88
Issue number1
DOIs
Publication statusPublished - 2007 Jul

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynaecology

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