Positive effect of whole-Body vibration loading on peri-Implant bone healing and implant osseointegration

Toru Ogawa, Xiaolei Zhang, Ignace Naert, Keiichi Sasaki, Joke Duyck

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)


The aim of this study was to evaluate the effect of low-magnitude, high-frequency (LMHF) loading, applied by means of whole body vibration (WBV), on peri-implant bone healing and implant osseointegration in rat tibiae. A custom-made titanium implant was inserted in the proximal metaphysis of the tibiae of male Wistar-rats. Animals were divided to unloaded control group and several test (loaded) groups received LMHF WBV loading with different loading parameters. Histological assessment was done combined with histomorphometrical measurements. Bone-to-implant contact (BIC) and peri-implant bone fraction (BF) were analyzed for histomorphometrical measurement. It was confirmed the bone stimulating potential of LMHF loading on peri-implant bone healing and implant osseointegration. Furthermore, time of loading signifi-cantly influenced the effect of the WBV on peri-implant bone healing. Twice short periods of loading appears to have the most favorable effect. In addition, loading parameters such as frequency and acceleration significantly influenced to the effect on peri-implant bone.

Original languageEnglish
Title of host publicationInterface Oral Health Science 2011
PublisherSpringer Japan
Number of pages3
ISBN (Electronic)9784431540700
ISBN (Print)9784431540694
Publication statusPublished - 2012 Jan 1


  • Low-magnitude and high-frequency loading
  • Oral implant
  • Peri-implant bone
  • Rat tibia
  • Whole body vibration

ASJC Scopus subject areas

  • Dentistry(all)


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