TY - GEN
T1 - Porous microneedle electrodes for the electrochemical sensing on skin
AU - Kai, Hiroyuki
N1 - Funding Information:
This work was partly supported by JST COI Grant Number JPMJCE1303 and MEXT/JSPS KAKENHI Grant Numbers 17K14096 and 19K15413. The author is grateful to The Kao Foundation for Arts and Sciences, The Nakatani Foundation for Advancement of Measuring Technologies in Biomedical Engineering, and Tanaka Kikinzoku Group for their financial support.
PY - 2019
Y1 - 2019
N2 - We report the fabrication of a porous microneedle electrode array whose outer and inner surfaces are coated with gold by electroless plating on a polymer material and its application to glucose sensing. The porous structure leads to a large surface area and therefore, the electrode could interface efficiently with interstitial fluid of skin. The prototype microneedle sensor was fabricated by modifying the microneedle electrode with glucose oxidase, which showed linear and sensitive amperometric response to glucose in solution. The gold-plated porous microneedles are potentially useful for the sensing of various molecules in interstitial fluid of skin.
AB - We report the fabrication of a porous microneedle electrode array whose outer and inner surfaces are coated with gold by electroless plating on a polymer material and its application to glucose sensing. The porous structure leads to a large surface area and therefore, the electrode could interface efficiently with interstitial fluid of skin. The prototype microneedle sensor was fabricated by modifying the microneedle electrode with glucose oxidase, which showed linear and sensitive amperometric response to glucose in solution. The gold-plated porous microneedles are potentially useful for the sensing of various molecules in interstitial fluid of skin.
KW - Glucose sensor
KW - Microneedle array
KW - Porous polymer monolith
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M3 - Conference contribution
AN - SCOPUS:85094978290
T3 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
SP - 699
EP - 700
BT - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PB - Chemical and Biological Microsystems Society
T2 - 23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
Y2 - 27 October 2019 through 31 October 2019
ER -