TY - JOUR
T1 - Porous carbon nanowire array for surface-enhanced Raman spectroscopy
AU - Chen, Nan
AU - Xiao, Ting Hui
AU - Luo, Zhenyi
AU - Kitahama, Yasutaka
AU - Hiramatsu, Kotaro
AU - Kishimoto, Naoki
AU - Itoh, Tamitake
AU - Cheng, Zhenzhou
AU - Goda, Keisuke
N1 - Funding Information:
This research was supported by JSPS Core-to-Core Program, JSPS KAKENHI (JP18K13798, JP20K14785), Murata Science Foundation, MEXT Q-LEAP Program, White Rock Foundation, University of Tokyo GAP Fund, National Natural Science Foundation of China (21671020, 61805175), Beijing Natural Science Foundation (2172049), KISTEC, Nakatani Foundation, and Ogasawara Foundation for the Promotion of Science and Engineering.
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for vibrational spectroscopy as it provides several orders of magnitude higher sensitivity than inherently weak spontaneous Raman scattering by exciting localized surface plasmon resonance (LSPR) on metal substrates. However, SERS can be unreliable for biomedical use since it sacrifices reproducibility, uniformity, biocompatibility, and durability due to its strong dependence on “hot spots”, large photothermal heat generation, and easy oxidization. Here, we demonstrate the design, fabrication, and use of a metal-free (i.e., LSPR-free), topologically tailored nanostructure composed of porous carbon nanowires in an array as a SERS substrate to overcome all these problems. Specifically, it offers not only high signal enhancement (~106) due to its strong broadband charge-transfer resonance, but also extraordinarily high reproducibility due to the absence of hot spots, high durability due to no oxidization, and high compatibility to biomolecules due to its fluorescence quenching capability.
AB - Surface-enhanced Raman spectroscopy (SERS) is a powerful tool for vibrational spectroscopy as it provides several orders of magnitude higher sensitivity than inherently weak spontaneous Raman scattering by exciting localized surface plasmon resonance (LSPR) on metal substrates. However, SERS can be unreliable for biomedical use since it sacrifices reproducibility, uniformity, biocompatibility, and durability due to its strong dependence on “hot spots”, large photothermal heat generation, and easy oxidization. Here, we demonstrate the design, fabrication, and use of a metal-free (i.e., LSPR-free), topologically tailored nanostructure composed of porous carbon nanowires in an array as a SERS substrate to overcome all these problems. Specifically, it offers not only high signal enhancement (~106) due to its strong broadband charge-transfer resonance, but also extraordinarily high reproducibility due to the absence of hot spots, high durability due to no oxidization, and high compatibility to biomolecules due to its fluorescence quenching capability.
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U2 - 10.1038/s41467-020-18590-7
DO - 10.1038/s41467-020-18590-7
M3 - Article
C2 - 32973145
AN - SCOPUS:85091434184
VL - 11
JO - Nature Communications
JF - Nature Communications
SN - 2041-1723
IS - 1
M1 - 4772
ER -