TY - JOUR
T1 - Poly(vinyl alcohol) gel ultrasound phantom with durability and visibility of internal flow
AU - Funamoto, Kenichi
AU - Yamashita, Osamu
AU - Hayase, Toshiyuki
N1 - Funding Information:
The authors are grateful for a grant for Research on Development of Systems and Technology for Advanced Measurement and Analysis, Japan Science Technology Agency. K.F. is grateful for a Grant-in-Aid for Young Scientists (start-up), JSPS (19860008), and a Grant-in-Aid for Young Scientists (B), JSPS (21700459). The authors acknowledge Prof. Tetsuya Kodama at the Graduate School of Biomedical Engineering, Tohoku University, for his help in ultrasound B-mode imaging of a mouse.
Publisher Copyright:
© 2014, The Japan Society of Ultrasonics in Medicine.
PY - 2014/1
Y1 - 2014/1
N2 - Purpose: Among various existing flow phantoms, none is characterized by appropriate acoustic, visibility, and durability properties simultaneously. The aim of this study was to develop a durable ultrasound phantom with visibility of the internal flow.Methods: Poly(vinyl alcohol) (PVA) gel was chosen as the basic material. The acoustic properties of various PVA gels were measured with 40-MHz ultrasound, the compositions of PVA, dimethyl sulfoxide (DMSO), and glass microbeads being changed, while visually checking the transparency. Wall-less ultrasound flow phantoms with a straight channel 2 mm in diameter were made from PVA gel, and ultrasound B-mode imaging was conducted with blood-mimicking fluid flow.Results: The acoustic properties of in vivo soft tissue were reproduced by PVA gel with a PVA concentration of 15 mass% and a glass microbead concentration of 2.9 mass% in a solvent of 98 mol% DMSO, showing acoustic properties of 1567 ± 4 m/s and 56 ± 5 dB/cm. The PVA gel was durable with visibility of the flow in the ultrasound phantom. The ultrasound B-mode image of the ultrasound flow phantom showed features approximating those of a mouse carotid artery.Conclusion: A durable PVA gel ultrasound phantom with visibility of the internal flow was developed.
AB - Purpose: Among various existing flow phantoms, none is characterized by appropriate acoustic, visibility, and durability properties simultaneously. The aim of this study was to develop a durable ultrasound phantom with visibility of the internal flow.Methods: Poly(vinyl alcohol) (PVA) gel was chosen as the basic material. The acoustic properties of various PVA gels were measured with 40-MHz ultrasound, the compositions of PVA, dimethyl sulfoxide (DMSO), and glass microbeads being changed, while visually checking the transparency. Wall-less ultrasound flow phantoms with a straight channel 2 mm in diameter were made from PVA gel, and ultrasound B-mode imaging was conducted with blood-mimicking fluid flow.Results: The acoustic properties of in vivo soft tissue were reproduced by PVA gel with a PVA concentration of 15 mass% and a glass microbead concentration of 2.9 mass% in a solvent of 98 mol% DMSO, showing acoustic properties of 1567 ± 4 m/s and 56 ± 5 dB/cm. The PVA gel was durable with visibility of the flow in the ultrasound phantom. The ultrasound B-mode image of the ultrasound flow phantom showed features approximating those of a mouse carotid artery.Conclusion: A durable PVA gel ultrasound phantom with visibility of the internal flow was developed.
KW - Acoustic properties
KW - Poly(vinyl alcohol) gel
KW - Tissue-mimicking material
KW - Ultrasound phantom
UR - http://www.scopus.com/inward/record.url?scp=84939890307&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84939890307&partnerID=8YFLogxK
U2 - 10.1007/s10396-014-0560-x
DO - 10.1007/s10396-014-0560-x
M3 - Article
C2 - 26578486
AN - SCOPUS:84939890307
VL - 42
SP - 17
EP - 23
JO - Journal of Medical Ultrasonics
JF - Journal of Medical Ultrasonics
SN - 1344-1388
IS - 1
ER -