Polycavernoside C and C2, the new analogs of the human lethal toxin polycavernoside A, from the red alga, Gracilaria edulis

Mari Yotsu-Yamashita, Kazumi Abe, Tetsuya Seki, Kenshu Fujiwara, Takeshi Yasumoto

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Two new analogs of the human lethal toxin polycavernoside A, polycavernoside C and C2 (0.1-0.2 mg for each), were isolated from the red alga, Gracilaria edulis. The relative stereostructure of polycavernoside C and the absolute structure of polycavernoside C2 were determined by spectroscopic analysis and synthesis of the model of their aglycon.

Original languageEnglish
Pages (from-to)2255-2259
Number of pages5
JournalTetrahedron Letters
Volume48
Issue number13
DOIs
Publication statusPublished - 2007 Mar 26

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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