Polyamines: Essential factors for growth and survival

T. Kusano, T. Berberich, C. Tateda, Y. Takahashi

    Research output: Contribution to journalReview article

    531 Citations (Scopus)

    Abstract

    Polyamines are low molecular weight, aliphatic polycations found in the cells of all living organisms. Due to their positive charges, polyamines bind to macromolecules such as DNA, RNA, and proteins. They are involved in diverse processes, including regulation of gene expression, translation, cell proliferation, modulation of cell signalling, and membrane stabilization. They also modulate the activities of certain sets of ion channels. Because of these multifaceted functions, the homeostasis of polyamines is crucial and is ensured through regulation of biosynthesis, catabolism, and transport. Through isolation of the genes involved in plant polyamine biosynthesis and loss-of-function experiments on the corresponding genes, their essentiality for growth is reconfirmed. Polyamines are also involved in stress responses and diseases in plants, indicating their importance for plant survival. This review summarizes the recent advances in polyamine research in the field of plant science compared with the knowledge obtained in microorganisms and animal systems.

    Original languageEnglish
    Pages (from-to)367-381
    Number of pages15
    JournalPlanta
    Volume228
    Issue number3
    DOIs
    Publication statusPublished - 2008 Aug 1

    Keywords

    • Growth
    • Homeostasis
    • Ion channel
    • Metabolism
    • Polyamine
    • Survival

    ASJC Scopus subject areas

    • Genetics
    • Plant Science

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  • Cite this

    Kusano, T., Berberich, T., Tateda, C., & Takahashi, Y. (2008). Polyamines: Essential factors for growth and survival. Planta, 228(3), 367-381. https://doi.org/10.1007/s00425-008-0772-7