Polarisation test and impedance measurement were performed on powder consolidated Zr-Al-Ni-Cu amorphous alloy with and without fibroblast L929 cells incubated in medium for 7 d. L929 cells show well extended morphology, indicating that the surface of the alloy does not show toxicity. L929 does not influence the values of cathodic and passive current densities and pitting potential of the alloy. Also, impedance behaviour is not changed with L929 cells. Those results indicate that the corrosion resistance of the powder consolidated Zr base amorphous alloy is not influenced with L929 cells. However, the pitting potential varies in the wide potential range regardless of the existence of L929 cells. Significant uniform corrosion sometimes occurs under impedance measurement at open circuit potential. It is supposed that the alloy becomes sensitive to electrochemical stimulation during the immersion in solution probably due to the defects such as grain boundary between original amorphous alloy powders. copyright The Electrochemical Society.