Poecillastrin D: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina

Daisaku Takemoto, Yoshihiko Takekawa, Rob W.M. Van Soest, Nobuhiro Fusetani, Shigeki Matsunaga

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.

Original languageEnglish
Pages (from-to)2697-2700
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number11
DOIs
Publication statusPublished - 2007

Keywords

  • Cytotoxic metabolite
  • Macrolide lactam
  • Marine sponge

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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