Poecillastrin D: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina

Daisaku Takemoto; Yoshihiko Takekawa; Rob W.M. Van Soest; Nobuhiro Fusetani; Shigeki Matsunaga

doi:10.1271/bbb.70293

Poecillastrin D: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina

Daisaku Takemoto, Yoshihiko Takekawa, Rob W.M. Van Soest, Nobuhiro Fusetani, Shigeki Matsunaga

Smart-Aging Research Center (SARC)

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.

Original language	English
Pages (from-to)	2697-2700
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	71
Issue number	11
DOIs	https://doi.org/10.1271/bbb.70293
Publication status	Published - 2007

Keywords

Cytotoxic metabolite
Macrolide lactam
Marine sponge

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

UN SDGs

This output contributes to the following Sustainable Development Goal(s)

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10.1271/bbb.70293

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title = "Poecillastrin D: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina",

abstract = "Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.",

keywords = "Cytotoxic metabolite, Macrolide lactam, Marine sponge",

author = "Daisaku Takemoto and Yoshihiko Takekawa and {Van Soest}, {Rob W.M.} and Nobuhiro Fusetani and Shigeki Matsunaga",

note = "Funding Information: Thanks are due to the crew of R/V Toyoshio-maru for their assistance in collecting the sponge. This work was partly supported by grant-in-aid for scientific research on priority areas 16073207 from MEXT and grants-in-aid for scientific research (B) 14360119 from JSPS.",

year = "2007",

doi = "10.1271/bbb.70293",

language = "English",

volume = "71",

pages = "2697--2700",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "11",

}

TY - JOUR

T1 - Poecillastrin D

T2 - A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina

AU - Takemoto, Daisaku

AU - Takekawa, Yoshihiko

AU - Van Soest, Rob W.M.

AU - Fusetani, Nobuhiro

AU - Matsunaga, Shigeki

N1 - Funding Information: Thanks are due to the crew of R/V Toyoshio-maru for their assistance in collecting the sponge. This work was partly supported by grant-in-aid for scientific research on priority areas 16073207 from MEXT and grants-in-aid for scientific research (B) 14360119 from JSPS.

PY - 2007

Y1 - 2007

N2 - Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.

AB - Poecillastrin D (2) was isolated together with poecillastrin C (1) from the deep sea sponge, Japsis serpentina. Its structure was elucidated to be that of a macrolide lactam by spectroscopic methods. These compounds showed potent cytotoxicity against various tumor cell lines.

KW - Cytotoxic metabolite

KW - Macrolide lactam

KW - Marine sponge

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DO - 10.1271/bbb.70293

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JO - Bioscience, Biotechnology and Biochemistry

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ER -

Poecillastrin D: A new cytotoxin of the chondropsin class from marine sponge Jaspis serpentina

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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