PMMA-based bone cements containing magnetite particles for the hyperthermia of cancer

M. Kawashita, K. Kawamura, Z. Li

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Polymethylmethacrylate-based cements containing magnetite (Fe 3O4) particles were prepared and their structure and properties were investigated. The Fe3O4 particles were uniformly dispersed in the cement matrix and constituted a maximum of 60 wt.% of the total weight of cement. The setting time of the cement increased and the maximum temperature during the setting reaction decreased with increasing Fe3O4 content. The compressive strength of cement increased with increasing Fe3O4 content. Cement with 50 wt.% Fe3O4 particles generated heat in alternating magnetic fields of 300 and 120 Oe at a frequency of 100 kHz.

Original languageEnglish
Pages (from-to)3187-3192
Number of pages6
JournalActa Biomaterialia
Volume6
Issue number8
DOIs
Publication statusPublished - 2010 Aug

Keywords

  • Alternating magnetic field
  • Hyperthermia
  • Magnetite
  • PMMA cement

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Biochemistry
  • Biomedical Engineering
  • Molecular Biology

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