Piperidine levels in the brain and peripheral organs in rats during cold exposure

T. Miyata, Y. Okano, K. Fukunaga, K. Iwasaki, K. Takahama, Y. Kasé

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Piperidine is one of biogenic amines possessing nicotine-like synaptotropic actions on the nervous systems. Since piperidine produces multiplex pharmacological actions, a role for the amine as a modulator in neuroendocrine as well as neuronal functions has been supposed. In the present study, piperidine levels in the brain and peripheral organs in rats during cold exposure were examined by use of a mass fragmentographic technique and it was found that piperidine concentrations in the brain and peripheral endocrine glands significantly increased at 180 min following exposure to 4°C. The significance of the findings is discussed with respect to the neurohormone-releasing effect of piperidine.

Original languageEnglish
Pages (from-to)323-327
Number of pages5
JournalLife Sciences
Volume28
Issue number3
DOIs
Publication statusPublished - 1981 Jan 19
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Pharmacology, Toxicology and Pharmaceutics(all)

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