Pinpoint keV/MeV x-ray sources for x-ray drug delivery system

M. Uesaka, K. Mizuno, A. Sakumi, J. Meiling, Noritaka Yusa, H. Takahashi, N. Nishiyama, K. Kataoka, K. Nakagawa

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Citations (Scopus)

Abstract

X-ray Drug Delivery System (DDS) is the most advanced radiation therapy coming after IMRT (Intensity Modulated Radiation Therapy) and IGRT (Image Guided). DDS uses advanced nano-scaled polymers which contain and deliver drug or contrast agent to cancers without side effects. Several X-ray DDS poses high-Z atoms like Pt and Au to absorb X-rays effectively and used as contrast agent for inspection. Moreover, they have radiation enhancement effect by emission of Auger electron and successive characteristic X-rays. The enhancement factor of Pt and Au is more than five. This can be used for therapy. This new modality must be very important for inspection and therapy of deep cancers. We are making use of our Compton scattering monochromatic keV X-ray source and MeV linac aspinpoint keV/MeV X-ray sources for the purpose. Physical analysis and evaluation of the contrast efficiency and radiation enhancement of the X-ray DDS are under way. Furthermore, a new compact X-band linac with a multi-beam klystron for a pinpoint X-ray source is proposed and designed. Updated research status and result are presented.

Original languageEnglish
Title of host publicationProceedings of the IEEE Particle Accelerator Conference, PAC07
Pages2793-2795
Number of pages3
DOIs
Publication statusPublished - 2007 Dec 1
Externally publishedYes
EventIEEE Particle Accelerator Conference, PAC07 - Albuquerque, NM, United States
Duration: 2007 Jun 252007 Jun 29

Publication series

NameProceedings of the IEEE Particle Accelerator Conference

Other

OtherIEEE Particle Accelerator Conference, PAC07
CountryUnited States
CityAlbuquerque, NM
Period07/6/2507/6/29

ASJC Scopus subject areas

  • Engineering(all)

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