Physical and specific crosslinking of collagen fibers by supramolecular nanogelators

Michiya Matsusaki; Ryotaro Amekawa; Masahiro Matsumoto; Yuji Tanaka; Akira Kubota; Kohji Nishida; Mitsuru Akashi

doi:10.1002/adma.201101284

Physical and specific crosslinking of collagen fibers by supramolecular nanogelators

Michiya Matsusaki, Ryotaro Amekawa, Masahiro Matsumoto, Yuji Tanaka, Akira Kubota, Kohji Nishida, Mitsuru Akashi

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Supramolecular nanogelators that possess triple-helices on their surfaces quickly form transparent hydrogels upon mixing with collagen solutions by hydrogen bonding. The exceptional selectivity of the gelation properties for fibrous collagens is observed, whereas other biomolecules exhibit no change. This material is useful as a smart injectable nanogelator with collagen specificity for tissue engineering.

Original language	English
Pages (from-to)	2957-2961
Number of pages	5
Journal	Advanced Materials
Volume	23
Issue number	26
DOIs	https://doi.org/10.1002/adma.201101284
Publication status	Published - 2011 Jul 12

Keywords

collagens
cornea
nanogelators
supramolecules
tissue engineering

ASJC Scopus subject areas

Materials Science(all)
Mechanics of Materials
Mechanical Engineering

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10.1002/adma.201101284

Cite this

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abstract = "Supramolecular nanogelators that possess triple-helices on their surfaces quickly form transparent hydrogels upon mixing with collagen solutions by hydrogen bonding. The exceptional selectivity of the gelation properties for fibrous collagens is observed, whereas other biomolecules exhibit no change. This material is useful as a smart injectable nanogelator with collagen specificity for tissue engineering.",

keywords = "collagens, cornea, nanogelators, supramolecules, tissue engineering",

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journal = "Advanced Materials",

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AU - Matsusaki, Michiya

AU - Amekawa, Ryotaro

AU - Matsumoto, Masahiro

AU - Tanaka, Yuji

AU - Kubota, Akira

AU - Nishida, Kohji

AU - Akashi, Mitsuru

PY - 2011/7/12

Y1 - 2011/7/12

N2 - Supramolecular nanogelators that possess triple-helices on their surfaces quickly form transparent hydrogels upon mixing with collagen solutions by hydrogen bonding. The exceptional selectivity of the gelation properties for fibrous collagens is observed, whereas other biomolecules exhibit no change. This material is useful as a smart injectable nanogelator with collagen specificity for tissue engineering.

AB - Supramolecular nanogelators that possess triple-helices on their surfaces quickly form transparent hydrogels upon mixing with collagen solutions by hydrogen bonding. The exceptional selectivity of the gelation properties for fibrous collagens is observed, whereas other biomolecules exhibit no change. This material is useful as a smart injectable nanogelator with collagen specificity for tissue engineering.

KW - collagens

KW - cornea

KW - nanogelators

KW - supramolecules

KW - tissue engineering

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JO - Advanced Materials

JF - Advanced Materials

SN - 0935-9648

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ER -

Physical and specific crosslinking of collagen fibers by supramolecular nanogelators

Abstract

Keywords

ASJC Scopus subject areas

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