A model far-red sensitive symmetrical squaraine dye (SQ-3) and unsymmetrical near infra-red sensitive cyanine dye (UCD-1) bearing direct-COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations including their interaction with bovine serum albumin (BSA) as a model protein in phosphate buffer solution (PBS). Both of the dyes exhibit strong interaction with BSA in phosphate buffer with high apparent binding constant. A judicious tuning of hydrophobic main backbone with reactive functionality for associative interaction with active site of BSA has been found to be necessary for BSA detection in PBS.
|Journal||Journal of Physics: Conference Series|
|Publication status||Published - 2016 Apr 19|
|Event||India-Japan Expert Group Meeting on Biomolecular Electronics and Organic Nanotechnology for Environment Preservation, IJEGMBE 2015 - Fukuoka, Japan|
Duration: 2015 Dec 23 → 2015 Dec 26
ASJC Scopus subject areas
- Physics and Astronomy(all)