Photochirogenesis with mutant human serum albumins: Enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate

Masaki Nishijima; Hanako Kato; Gaku Fukuhara; Cheng Yang; Tadashi Mori; Toru Maruyama; Masaki Otagiri; Yoshihisa Inoue

doi:10.1039/c3cc42656d

Photochirogenesis with mutant human serum albumins: Enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate

Masaki Nishijima, Hanako Kato, Gaku Fukuhara, Cheng Yang, Tadashi Mori, Toru Maruyama, Masaki Otagiri, Yoshihisa Inoue

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75–85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability.

Original language	English
Pages (from-to)	7433-7435
Number of pages	3
Journal	Chemical Communications
Volume	49
Issue number	67
DOIs	https://doi.org/10.1039/c3cc42656d
Publication status	Published - 2013 Jul 25
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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10.1039/c3cc42656d

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abstract = "Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75–85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability.",

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T2 - Enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate

AU - Nishijima, Masaki

AU - Kato, Hanako

AU - Fukuhara, Gaku

AU - Yang, Cheng

AU - Mori, Tadashi

AU - Maruyama, Toru

AU - Otagiri, Masaki

AU - Inoue, Yoshihisa

PY - 2013/7/25

Y1 - 2013/7/25

N2 - Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75–85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability.

AB - Mutant human serum albumins accelerated the photocyclodimerization of 2-anthracenecarboxylate to afford chiral cyclodimers in 75–85% enantiomeric excesses, revealing that the mutations to impair non-productive sites 1 and/or 2 enhanced the substrate binding to site 3 without seriously damaging its inherently high photochirogenic ability.

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Photochirogenesis with mutant human serum albumins: Enantiodifferentiating photocyclodimerization of 2-anthracenecarboxylate

Abstract

ASJC Scopus subject areas

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