Photochemistry of benzophenone immobilized in a major groove of DNA: Formation of thermally reversible interstrand cross-link

Kazuhiko Nakatani, Takashi Yoshida, Isao Saito

Research output: Contribution to journalArticlepeer-review

49 Citations (Scopus)

Abstract

We here report a highly site and sequence selective formation of an interstrand cross-link of BPU-containing oligomer duplexes. The cross-link was found spontaneously reverted to original oligomers upon heating, providing a new method for the temporary connection of two DNA strands.

Original languageEnglish
Pages (from-to)2118-2119
Number of pages2
JournalJournal of the American Chemical Society
Volume124
Issue number10
DOIs
Publication statusPublished - 2002 Mar 13
Externally publishedYes

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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