Phase-contrast X-ray imaging with a large monolithic X-ray interferometer

Tohoru Takeda, Atsushi Momose, Quanwen Yu, Jin Wu, Keiichi Hirano, Yuji Itai

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)


To increase the field of view for large objects in phase-contrast X-ray imaging, a large monolithic X-ray interferometer has been fabricated using an available silicon ingot of diameter 10 cm. A performance study of this interferometer has been carried out using a synchrotron X-ray source. The view size of the interference pattern obtained with this interferometer was 25 mm wide and 15 mm high and its visibility was 79%. Various structures of a sliced human hepatocellular carcinoma were identified as necrosis, hemorrhagic necrosis, normal liver tissue and blood vessel. The performance of this interferometer was sufficient for phase-contrast X-ray imaging.

Original languageEnglish
Pages (from-to)280-282
Number of pages3
JournalJournal of Synchrotron Radiation
Issue number4
Publication statusPublished - 2000 Jul 1
Externally publishedYes


  • Cancer
  • Diagnostic radiology
  • Monolithic x-ray interferometer
  • Phase-contrast x-ray imaging

ASJC Scopus subject areas

  • Radiation
  • Nuclear and High Energy Physics
  • Instrumentation


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