Phase-Contrast Radiographs of Nonstained Rat Cerebellar Specimen

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254 Citations (Scopus)

Abstract

Phase-contrast radiography using an x-ray interferometer is presented for observing organic matter. High sensitivity of phase-contrast radiography is demonstrated with a rat cerebellar specimen without staining it with a contrast medium. The layer structure of the cerebellum can be observed in the obtained image while there is no clear structure in the corresponding absorption-contrast image. Quantitative image analysis is made possible by converting an x-ray interference pattern to an x-ray phase shift distribution. The lipid distribution in the cerebellum is discussed by evaluating x-ray phase shifts before and after lipid removal.

Original languageEnglish
Pages (from-to)375-379
Number of pages5
JournalMedical Physics
Volume22
Issue number4
DOIs
Publication statusPublished - 1995 Apr
Externally publishedYes

Keywords

  • cerebellum
  • lipid
  • phase contrast
  • radiography
  • x-rays

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

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