Phaeohyphomycosis caused by phaeoacremoniumrubrigenum in an immunosuppressive patient: A case report and review of the literature

Sadanori Furudate, Shu Sasai, Yukikazu Numata, Taku Fujimura, Setsuya Aiba

Research output: Contribution to journalReview article

10 Citations (Scopus)

Abstract

Phaeohyphomycosis (PHM) is a rare, deep fungal infection of the skin and subcutaneous tissues caused by dematiaceous fungi. In this report, we describe a case of PHM caused by Phaeoacremoniumrubrigenum, which is generally known to infect woody plants. We detected the gray-blackish villi by biopsy culture material, and slide culture revealed the conidia arising from slightly tapering phialides. Furthermore, we differentiated these fungi as P.rubrigenum by Basic Local Alignment Search Tool (BLAST) algorithm. We performed surgical debridement of disseminated nodules and administered oral itraconazole for a duration of 4 weeks. One year after stopping itraconazole, there was no sign of relapsing subcutaneous nodules. To our knowledge, this is the third case report of PHM developing from skin infection by P. rubrigenum in human.

Original languageEnglish
Pages (from-to)119-124
Number of pages6
JournalCase Reports in Dermatology
Volume4
Issue number2
DOIs
Publication statusPublished - 2012 May

Keywords

  • Adult Still's disease
  • Phaeoacremoniumrubrigenum
  • Phaeohyphomycosis

ASJC Scopus subject areas

  • Dermatology

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