Abstract
Positron emission tomography dynamic studies have been performed to quantify several biomedical functions. In a quantitative analysis of these studies, kinetic parameters were estimated by mathematical methods, such as a nonlinear least-squares algorithm with compartmental model and graphical analysis. In this estimation, the uncertainty in the estimated kinetic parameters depends on the signal-to-noise ratio and quantitative analysis method. This review describes the reliability of parameter estimates for various analysis methods in reversible and irreversible models.
Original language | English |
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Pages (from-to) | 1-11 |
Number of pages | 11 |
Journal | Annals of Nuclear Medicine |
Volume | 22 |
Issue number | 1 |
DOIs | |
Publication status | Published - 2008 Jan 1 |
Externally published | Yes |
Keywords
- Compartmental model
- Error analysis
- PET
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging