PET kinetic analysis - Compartmental model

Hiroshi Watabe, Yoko Ikoma, Yuichi Kimura, Mika Naganawa, Miho Shidahara

Research output: Contribution to journalReview article

110 Citations (Scopus)

Abstract

PET enables not only visualization of the distribution of radiotracer, but also has ability to quantify several biomedical functions. Compartmental model is a basic idea to analyze dynamic PET data. This review describes the principle of the compartmental model and categorizes the techniques and approaches for the compartmental model according to various aspects: model design, experimental design, invasiveness, and mathematical solution. We also discussed advanced applications of the compartmental analysis with PET.

Original languageEnglish
Pages (from-to)583-588
Number of pages6
JournalAnnals of Nuclear Medicine
Volume20
Issue number9
DOIs
Publication statusPublished - 2006 Dec 27
Externally publishedYes

Keywords

  • Compartmental model
  • PET
  • Pharmacokinetics

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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