Permeation of manganese, cadmium, zinc, and beryllium through calcium channels of an insect muscle membrane

Jun Fukuda, Kazuyoshi Kawa

Research output: Contribution to journalArticlepeer-review

75 Citations (Scopus)

Abstract

Larval muscle fibers of a beetle, Xylotrupes dichotomus, produce calcium spikes that are maintained when the fibers are bathed in saline solutions containing manganese, cadmium, zinc, or beryllium instead of calcium. This indicates that these cations permeate the calcium channels of the muscle fiber. By contrast, cobalt, nickel, and magnesium are nonpermeating and behave as competitive inhibitors of the permeation of the other divalent cations. Some of the permeating cations suppress delayed rectification.

Original languageEnglish
Pages (from-to)309-311
Number of pages3
JournalScience
Volume196
Issue number4287
DOIs
Publication statusPublished - 1977 Jan 1

ASJC Scopus subject areas

  • General

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