Perivascular coating with fibrin glue of cerebral arteries in patients with aneurysmal subarachnoid hemorrhage; incidence of chronic hydrocephalus

Miki Fujimura, Takayuki Sugawara, Hirobumi Seki, Tatsuya Oku, Kaku Niimura, Yasunari Otawara, Hiroshi Higuchi

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

The incidence of chronic hydrocephalus was studied in 39 patients with subarachnoid hemorrhage, who underwent perivascular coating with fibrin glue of cerebral arteries after clipping of aneurysm. A use was made of this procedure in order to prevent vasospasm by keeping the main cerebral arteries away from direct contact with subarachnoid clots. Most cases in this series belonged to group 3 of Fisher's CT grade (33/39, 84.6%). As a result, despite the high CT grade, the incidence of chronic hydrocephalus was as low as 17.9% (7/39), almost in agreement with those of the previous literature. In conclusion, (1) coating with fibrin glue did not increase the incidence of chronic hydrocephalus and (2) intrathecal application of fibrin glue is a promising method in the field of clinical neurosurgery.

Original languageEnglish
Pages (from-to)267-272
Number of pages6
JournalTohoku Journal of Experimental Medicine
Volume179
Issue number4
DOIs
Publication statusPublished - 1996 Aug

Keywords

  • Fibrin glue
  • Hydrocephalus
  • Subarachnoid hemorrhage (SAH)
  • Vasospasm

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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