TY - JOUR
T1 - Performance of using opposing homozygotes for paternity testing in Japanese Black cattle
AU - Komiya, Ryota
AU - Ogawa, Shinichiro
AU - Aonuma, Tatsuya
AU - Satoh, Masahiro
N1 - Funding Information:
We thank the anonymous reviewers for their valuable suggestions.
Publisher Copyright:
© 2021 Wiley-VCH GmbH
PY - 2022/1
Y1 - 2022/1
N2 - Genome-wide single nucleotide polymorphism (SNP) markers in Japanese Black cattle enable genomic prediction and verifying parent–offspring relationships. We assessed the performance of opposing homozygotes (OH) for paternity testing in Japanese Black cattle, using SNP genotype information of 50 sires and 3,420 fattened animals, 1,945 of which were fathered by the 50 genotyped sires. The number of OH was counted for each sire–progeny pair in 28,764 SNPs with minor allele frequencies of ≥0.05 in this population. Across all pairs of animals, the number of OH tended to increase as the pedigree-based coefficient of relationship decreased. With a threshold of 288 (1% of SNPs) for paternity testing, most sire–progeny pairs were detected as true relationships. The frequency of Mendelian inconsistencies was 2.4%, reflecting the high accuracy of pedigree information in Japanese Black cattle population. The results indicate the utility of OH for paternity testing in Japanese Black cattle.
AB - Genome-wide single nucleotide polymorphism (SNP) markers in Japanese Black cattle enable genomic prediction and verifying parent–offspring relationships. We assessed the performance of opposing homozygotes (OH) for paternity testing in Japanese Black cattle, using SNP genotype information of 50 sires and 3,420 fattened animals, 1,945 of which were fathered by the 50 genotyped sires. The number of OH was counted for each sire–progeny pair in 28,764 SNPs with minor allele frequencies of ≥0.05 in this population. Across all pairs of animals, the number of OH tended to increase as the pedigree-based coefficient of relationship decreased. With a threshold of 288 (1% of SNPs) for paternity testing, most sire–progeny pairs were detected as true relationships. The frequency of Mendelian inconsistencies was 2.4%, reflecting the high accuracy of pedigree information in Japanese Black cattle population. The results indicate the utility of OH for paternity testing in Japanese Black cattle.
KW - Japanese Black cattle
KW - opposing homozygotes
KW - paternity testing
KW - pedigree
KW - single nucleotide polymorphism
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U2 - 10.1111/jbg.12649
DO - 10.1111/jbg.12649
M3 - Article
C2 - 34499371
AN - SCOPUS:85114494335
VL - 139
SP - 113
EP - 124
JO - Journal of Animal Breeding and Genetics
JF - Journal of Animal Breeding and Genetics
SN - 0931-2668
IS - 1
ER -