Pathomechanism and prevalence of sporadic inclusion body myositis (sIBM)

Naoki Suzuki, Maki Tateyama, Hitoshi Warita, Rumiko Izumi, Ichizo Nishino, Masashi Aoki

Research output: Contribution to journalArticle

Abstract

Sporadic inclusion body myositis (sIBM) is an intractable and progressive skeletal muscle disease of unknown cause and without effective treatment. The etiology of sIBM is still unknown, however genetic factors, aging, life styles, environmental factors may be involved. sIBM is generally refractory to current therapy, such as steroid or immunosuppressants. To elucidate the pathomechanism of sIBM is the most important way to make therapeutic approach. In this review we estimated the prevalence of sIBM in Japan and discuss the pathomechanism of sIBM.

Original languageEnglish
Pages (from-to)964-966
Number of pages3
JournalClinical Neurology
Volume51
Issue number11
DOIs
Publication statusPublished - 2011 Dec 1

Keywords

  • Inflammation
  • Muscle pathology
  • Prevalence
  • Rimmed vacuole
  • Sporadic inclusion body myositis (sIBM)

ASJC Scopus subject areas

  • Clinical Neurology

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