Parapharyngeal neuroglial heterotopia appearing as high uptake on 18 F–FDG PET: case report and literature review of radiographical findings

Masayuki Kameyama, Tomohiro Kawaguchi, Hidetaka Niizuma, Takenori Ogawa, Kenichi Watanabe, Toshiaki Hayashi, Kanako Sato, Masayuki Kanamori, Mika Watanabe, Yukio Katori, Shigeo Kure, Teiji Tominaga

Research output: Contribution to journalArticlepeer-review


Parapharyngeal neuroglial heterotopia is a rare entity, and the specific radiographical findings are unclear. We present a case of parapharyngeal neuroglial heterotopia examined with proton magnetic resonance spectroscopy ( 1 H–MRS) and 18 F–fluorodesoxyglucose positron emission tomography ( 18 F–FDG PET). Our neonate patient presented with neck mass and polyhydramnios during gestation. Computed tomography and magnetic resonance imaging demonstrated the morphological characteristics, but failed to establish the diagnosis. 1 H–MRS showed a non-malignant pattern, but 18 F–FDG PET demonstrated high glucose metabolism. Complete resection was achieved and the histopathological diagnosis was neuroglial heterotopia. Assessment of biological activity may be useful for both preoperative diagnosis and postoperative evaluation of residual lesions.

Original languageEnglish
Pages (from-to)801-809
Number of pages9
JournalActa neurochirurgica
Issue number4
Publication statusPublished - 2018 Apr 1


  • Differential diagnosis
  • F–FDG pet
  • H–MRS
  • Neuroglial heterotopia

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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