Palladium(0)-catalyzed condensation of bromopyridines with α-substituted acetonitriles

Takao Sakamoto; Eisaku Katoh; Yoshinori Kondo; Hiroshi Yamanaka

Palladium(0)-catalyzed condensation of bromopyridines with α-substituted acetonitriles

Takao Sakamoto, Eisaku Katoh, Yoshinori Kondo, Hiroshi Yamanaka

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

The condensation of bromopyridines with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in the presence of tetrakis(triphenylphosphine) palladium in 1,2-dimethoxyethane gave the corresponding α-substituted pyridineacetonitrile derivatives in good yields.

Original language	English
Pages (from-to)	1353-1356
Number of pages	4
Journal	Heterocycles
Volume	27
Issue number	6
Publication status	Published - 1988 Jun 1

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

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title = "Palladium(0)-catalyzed condensation of bromopyridines with α-substituted acetonitriles",

abstract = "The condensation of bromopyridines with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in the presence of tetrakis(triphenylphosphine) palladium in 1,2-dimethoxyethane gave the corresponding α-substituted pyridineacetonitrile derivatives in good yields.",

author = "Takao Sakamoto and Eisaku Katoh and Yoshinori Kondo and Hiroshi Yamanaka",

year = "1988",

month = jun,

day = "1",

language = "English",

volume = "27",

pages = "1353--1356",

journal = "Heterocycles",

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publisher = "Japan Institute of Heterocyclic Chemistry",

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TY - JOUR

T1 - Palladium(0)-catalyzed condensation of bromopyridines with α-substituted acetonitriles

AU - Sakamoto, Takao

AU - Katoh, Eisaku

AU - Kondo, Yoshinori

AU - Yamanaka, Hiroshi

PY - 1988/6/1

Y1 - 1988/6/1

N2 - The condensation of bromopyridines with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in the presence of tetrakis(triphenylphosphine) palladium in 1,2-dimethoxyethane gave the corresponding α-substituted pyridineacetonitrile derivatives in good yields.

AB - The condensation of bromopyridines with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in the presence of tetrakis(triphenylphosphine) palladium in 1,2-dimethoxyethane gave the corresponding α-substituted pyridineacetonitrile derivatives in good yields.

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M3 - Article

AN - SCOPUS:0000583866

VL - 27

SP - 1353

EP - 1356

JO - Heterocycles

JF - Heterocycles

SN - 0385-5414

IS - 6

ER -