Palladium(0)-catalyzed condensation of bromopyridines with α-substituted acetonitriles

Takao Sakamoto, Eisaku Katoh, Yoshinori Kondo, Hiroshi Yamanaka

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)

Abstract

The condensation of bromopyridines with the sodium salts of phenylsulfonylacetonitrile and diethyl cyanomethylphosphonate in the presence of tetrakis(triphenylphosphine) palladium in 1,2-dimethoxyethane gave the corresponding α-substituted pyridineacetonitrile derivatives in good yields.

Original languageEnglish
Pages (from-to)1353-1356
Number of pages4
JournalHeterocycles
Volume27
Issue number6
Publication statusPublished - 1988 Jun 1

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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