Abstract
Palladium-catalysed silylation of aryl iodides with electron-withdrawing groups was efficiently achieved using pyridine and lithium chloride as additives and conducting the reaction at room temperature. Functionalized aryl[2-(hydroxymethyl)-phenyl]dimethylsilanes were also prepared by palladium-catalysed reaction using THP-protected [2-(hydroxymethyl)-phenyl] dimethylsilane as a silylating agent followed by deprotection. Rhodium-catalysed 1,4-addition of the arylsilane was carried out using cyclohexenone as an enone in excellent yield.
Original language | English |
---|---|
Pages (from-to) | 1161-1163 |
Number of pages | 3 |
Journal | European Journal of Organic Chemistry |
Issue number | 7 |
DOIs | |
Publication status | Published - 2008 Mar 1 |
Keywords
- Aryl iodides
- Lithium chloride
- Palladium
- Pyridine
- Silylation
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry