Palladium-catalyzed addition of alcohol pronucleophiles 1 to alkylidenecyclopropane derivatives afforded the corresponding allylic ethers 3 in excellent to moderate yields. Catalyst optimization indicated the Pd(PPh3)4-P(o-tolyl)3 combination as the best system among all catalysts tested. Intramolecular reaction also proceeded smoothly. A plausible mechanism for this catalytic reaction was proposed.
ASJC Scopus subject areas
- Organic Chemistry