Palladium-catalyzed [3+2] cycloaddition of alkylidenecyclopropanes with imines

Byoung Ho Oh, Itaru Nakamura, Shinichi Saito, Yoshinori Yamamoto

Research output: Contribution to journalArticlepeer-review

88 Citations (Scopus)

Abstract

Alkylidenecyclopropanes react with N-tosylimines in toluene in the presence of a catalytic amount of Pd(PPh3)4 to afford the corresponding [3+2] cycloaddition products, pyrrolidine derivatives, in good to excellent yields.

Original languageEnglish
Pages (from-to)6203-6205
Number of pages3
JournalTetrahedron Letters
Volume42
Issue number35
DOIs
Publication statusPublished - 2001 Aug 27

Keywords

  • Alkylidenecyclopropane
  • Cycloaddition
  • Imine
  • Palladium catalysts
  • Pyrrolidine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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