p53 Mutation does not determine prognosis in non-hodgkin's lymphoma

M. Osada, C. Ishioka, Y. Murakawa, R. Ichinohasama, R. Kanamaru, S. Ikawa

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

We studied the clinical significance of the extent of p53 protein expression by immunohistochemical analysis and p53 mutations by functional analysis of p53 in 42 patients with high and intermediate grade of Non- Hodgkin's Lymphoma (NHL). Neither p53 expression nor mutation correlated with short survival or resistance to chemoradiotherapy, implying that p53 mutation is not a prognostic factor in NHL.

Original languageEnglish
Pages (from-to)471-475
Number of pages5
JournalJapanese Journal of Cancer and Chemotherapy
Volume24
Issue number4
Publication statusPublished - 1997 Sep 24

Keywords

  • FASAY
  • Non-Hodgkin's lymphoma
  • p53

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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