TY - JOUR
T1 - Oxygenation to bovine blood in artificial heart and lung using vibrating flow pump
AU - Shintaku, Hirofumi
AU - Yonemura, Tsubasa
AU - Isoyama, Takashi
AU - Yambe, Tomoyuki
AU - Kawano, Satoyuki
N1 - Copyright:
Copyright 2020 Elsevier B.V., All rights reserved.
PY - 2008/4
Y1 - 2008/4
N2 - We had developed the vibrating flow pump (VFP) for left ventricular assist device based on the fluid dynamical analysis and the animal tests. The main advantages of VFP were generating the oscillated blood flow and having simple mechanical structure. In this study, we constructed an experimental apparatus for a prototype artificial heart and lung by means of installing hollow fibers into the vibrating tube in the VFP. The characteristics of gas exchange were investigated both by experiment using bovine blood and by numerical analysis. The unsteady, incompressible, and axisymmetric Navier-Stokes equations and diffusion equation were solved based on finite difference technique. In the prototype VFP, the effect of the oscillated flow on the gas exchange was relatively small in the range of Reynolds number of O (1) - O (1000). Comparing experimental and numerical results, we discussed the validity of the numerical analysis and predicted the characteristics of the VFP. The basic design data of VFP installing hollow fibers were accumulated for the artificial heart and lung.
AB - We had developed the vibrating flow pump (VFP) for left ventricular assist device based on the fluid dynamical analysis and the animal tests. The main advantages of VFP were generating the oscillated blood flow and having simple mechanical structure. In this study, we constructed an experimental apparatus for a prototype artificial heart and lung by means of installing hollow fibers into the vibrating tube in the VFP. The characteristics of gas exchange were investigated both by experiment using bovine blood and by numerical analysis. The unsteady, incompressible, and axisymmetric Navier-Stokes equations and diffusion equation were solved based on finite difference technique. In the prototype VFP, the effect of the oscillated flow on the gas exchange was relatively small in the range of Reynolds number of O (1) - O (1000). Comparing experimental and numerical results, we discussed the validity of the numerical analysis and predicted the characteristics of the VFP. The basic design data of VFP installing hollow fibers were accumulated for the artificial heart and lung.
KW - Artificial heart
KW - Bio-fluid mechanics
KW - Computational fluid dynamics
KW - Gas exchange
KW - Oscillatory flow
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U2 - 10.1299/kikaib.74.862
DO - 10.1299/kikaib.74.862
M3 - Article
AN - SCOPUS:48249085823
VL - 74
SP - 862
EP - 870
JO - Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
JF - Nihon Kikai Gakkai Ronbunshu, B Hen/Transactions of the Japan Society of Mechanical Engineers, Part B
SN - 0387-5016
IS - 4
ER -