Quinones are ubiquitously present in the environment. This review summarizes the cellular toxicity of 9,10-phenanthraquinone (9,10-PQ), a component of diesel exhaust particles, and the cytoprotective mechanism of the nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) system against oxidative stress exerted by 9,10-PQ.
- Nuclear factor erythroid 2-related factor 2
- Oxidative stress
ASJC Scopus subject areas
- Health, Toxicology and Mutagenesis