Oxidative stress-dependent cellular toxicity and cytoprotection during exposure to 9,10-phenanthraquinone, a component of diesel exhaust particles

Research output: Contribution to journalShort surveypeer-review

2 Citations (Scopus)

Abstract

Quinones are ubiquitously present in the environment. This review summarizes the cellular toxicity of 9,10-phenanthraquinone (9,10-PQ), a component of diesel exhaust particles, and the cytoprotective mechanism of the nuclear factor erythroid 2-related factor 2 (Nrf2)/Kelch-like ECH-associated protein 1 (Keap1) system against oxidative stress exerted by 9,10-PQ.

Original languageEnglish
Pages (from-to)347-350
Number of pages4
JournalJournal of Health Science
Volume55
Issue number3
DOIs
Publication statusPublished - 2009 Jun

Keywords

  • Cytoprotection
  • Detoxification
  • Nuclear factor erythroid 2-related factor 2
  • Oxidative stress
  • Quinone

ASJC Scopus subject areas

  • Toxicology
  • Health, Toxicology and Mutagenesis

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