Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae

Tsutomu Takahashi, Toomi Yano, Jun Xuan Zhu, Gi Wook Hwang, Akira Naganuma

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

To elucidate mechanisms of arsenic toxicity and biological defense mechanisms against arsenic, we searched for genes that, when overexpressed, conferred arsenite resistance on yeast. Employing a Saccharomyces cerevisiae open reading frame (ORF) library, four genes associated with arsenite resistance, FAP7, MIG3, TMA19, and YLR392c, were identified.

Original languageEnglish
Pages (from-to)945-946
Number of pages2
JournalJournal of Toxicological Sciences
Volume35
Issue number6
DOIs
Publication statusPublished - 2010 Dec 1

Keywords

  • Arsenite
  • Fap7
  • Mig3
  • Resistance
  • Yeast

ASJC Scopus subject areas

  • Toxicology

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