Overexpression of FAP7, MIG3, TMA19, or YLR392c confers resistance to arsenite on Saccharomyces cerevisiae

Tsutomu Takahashi, Toomi Yano, Jun Xuan Zhu, Gi Wook Hwang, Akira Naganuma

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

To elucidate mechanisms of arsenic toxicity and biological defense mechanisms against arsenic, we searched for genes that, when overexpressed, conferred arsenite resistance on yeast. Employing a Saccharomyces cerevisiae open reading frame (ORF) library, four genes associated with arsenite resistance, FAP7, MIG3, TMA19, and YLR392c, were identified.

Original languageEnglish
Pages (from-to)945-946
Number of pages2
JournalJournal of Toxicological Sciences
Volume35
Issue number6
DOIs
Publication statusPublished - 2010 Dec

Keywords

  • Arsenite
  • Fap7
  • Mig3
  • Resistance
  • Yeast

ASJC Scopus subject areas

  • Toxicology

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