Orientation control of self-stacking D,L-alternating cyclic octa-α-peptide through multiple electrostatic interactions

Kazutoshi Murota; Seiji Sakamoto; Kazuaki Kudo

doi:10.1246/cl.2007.1070

Orientation control of self-stacking D,L-alternating cyclic octa-α-peptide through multiple electrostatic interactions

Kazutoshi Murota, Seiji Sakamoto, Kazuaki Kudo

Division of Organic- and Biomaterials Research

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We designed D,L-alternating cyclic octa-α-peptides having two D-lysines and two D-glutamates as electrostatically interacting units in order to regulate the orientation of the peptide units upon stacking in an antiparallel manner. Spectroscopic analyses of the fluorescence probe on the peptide indicated the successful control of the orientation.

Original language	English
Pages (from-to)	1070-1071
Number of pages	2
Journal	Chemistry Letters
Volume	36
Issue number	8
DOIs	https://doi.org/10.1246/cl.2007.1070
Publication status	Published - 2007 Aug 5

ASJC Scopus subject areas

Chemistry(all)

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abstract = "We designed D,L-alternating cyclic octa-α-peptides having two D-lysines and two D-glutamates as electrostatically interacting units in order to regulate the orientation of the peptide units upon stacking in an antiparallel manner. Spectroscopic analyses of the fluorescence probe on the peptide indicated the successful control of the orientation.",

author = "Kazutoshi Murota and Seiji Sakamoto and Kazuaki Kudo",

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AU - Sakamoto, Seiji

AU - Kudo, Kazuaki

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Y1 - 2007/8/5

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AB - We designed D,L-alternating cyclic octa-α-peptides having two D-lysines and two D-glutamates as electrostatically interacting units in order to regulate the orientation of the peptide units upon stacking in an antiparallel manner. Spectroscopic analyses of the fluorescence probe on the peptide indicated the successful control of the orientation.

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JF - Chemistry Letters

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Orientation control of self-stacking D,L-alternating cyclic octa-α-peptide through multiple electrostatic interactions

Abstract

ASJC Scopus subject areas

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