Organozinc reagents in DMSO solvent: Remarkable promotion of S N2′ reaction for allene synthesis

Koji Kobayashi, Hiroshi Naka, Andrew E.H. Wheatley, Yoshinori Kondo

Research output: Contribution to journalArticlepeer-review

41 Citations (Scopus)

Abstract

(Chemical Equation Presented) The SN2′ reaction of propragyl mesylates with organozinc reagents was dramatically improved in DMSO solvent, and the stereoselective conversion of chiral substrates was successfully achieved using LiCl-free diorganozinc without the loss of optical purity.

Original languageEnglish
Pages (from-to)3375-3377
Number of pages3
JournalOrganic letters
Volume10
Issue number15
DOIs
Publication statusPublished - 2008 Dec 1

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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