TY - GEN
T1 - Organic skin patch with built-in enzymatic battery
AU - Nishizawa, Matsuhiko
AU - Nagamine, Kuniaki
AU - Kai, Hiroyuki
PY - 2016/2/26
Y1 - 2016/2/26
N2 - We have achieved development of a completely organic, totally disposable iontophoresis patch with a built-in enzymatic biofuel cells (BFCs) that utilizes enzymes as electrocatalysts, which can work under mild conditions, i.e., body temperature and at approximately neutral pH. We used fructose as the fuel because the enzyme for oxidation of fructose (fructose dehydrogenese, FDH) can work without the presence of electron mediators for electrocatalysis, resulting in a simple configuration of the patch. The patch, when mounted on the skin, generates a transdermal ionic current with the osmotic flow from anode to cathode, thereby administrating the chemical into the skin.
AB - We have achieved development of a completely organic, totally disposable iontophoresis patch with a built-in enzymatic biofuel cells (BFCs) that utilizes enzymes as electrocatalysts, which can work under mild conditions, i.e., body temperature and at approximately neutral pH. We used fructose as the fuel because the enzyme for oxidation of fructose (fructose dehydrogenese, FDH) can work without the presence of electron mediators for electrocatalysis, resulting in a simple configuration of the patch. The patch, when mounted on the skin, generates a transdermal ionic current with the osmotic flow from anode to cathode, thereby administrating the chemical into the skin.
UR - http://www.scopus.com/inward/record.url?scp=84970965873&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84970965873&partnerID=8YFLogxK
U2 - 10.1109/MEMSYS.2016.7421672
DO - 10.1109/MEMSYS.2016.7421672
M3 - Conference contribution
AN - SCOPUS:84970965873
T3 - Proceedings of the IEEE International Conference on Micro Electro Mechanical Systems (MEMS)
SP - 505
EP - 508
BT - MEMS 2016 - 29th IEEE International Conference on Micro Electro Mechanical Systems
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 29th IEEE International Conference on Micro Electro Mechanical Systems, MEMS 2016
Y2 - 24 January 2016 through 28 January 2016
ER -