Organ-explanted bionic simulator (OBiS): Concurrent microcardiovascular anastomosis of chick embryo

Hirofumi Owaki, Taisuke Masuda, Tomohiro Kawahara, Natsuki Takei, Keiko Miwa-Kodama, Kota Miyasaka, Toshihiko Ogura, Fumihito Arai

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

In this paper, we newly propose an organ-explanted bionic simulator (OBiS) using an isolated organ tissue. We use a heart isolated from the chick embryo for proposed simulator. To achieve the OBiS, we perform the concurrent microvascular anastomosis by using suction-induced vascular fixation (SVF) method for easily connection to artificial tubes with blood vessels led to the explanted chick's heart. Through the experiment with a simulated cardiovascular, it is confirmed that vessels can be aligned by using the proposed method. In addition, we have succeeded in connecting the Alg tubes with the blood vessels led to the heart of chick embryo. OBiS is available for the evaluation of new drugs immune response not only without using large animals but also as a response of organs beyond cellular level.

Original languageEnglish
Title of host publication2012 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2012
Pages3812-3817
Number of pages6
DOIs
Publication statusPublished - 2012 Dec 1
Event25th IEEE/RSJ International Conference on Robotics and Intelligent Systems, IROS 2012 - Vilamoura, Algarve, Portugal
Duration: 2012 Oct 72012 Oct 12

Publication series

NameIEEE International Conference on Intelligent Robots and Systems
ISSN (Print)2153-0858
ISSN (Electronic)2153-0866

Other

Other25th IEEE/RSJ International Conference on Robotics and Intelligent Systems, IROS 2012
CountryPortugal
CityVilamoura, Algarve
Period12/10/712/10/12

ASJC Scopus subject areas

  • Control and Systems Engineering
  • Software
  • Computer Vision and Pattern Recognition
  • Computer Science Applications

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