TY - GEN
T1 - Organ-explanted bionic simulator (OBiS)
T2 - 25th IEEE/RSJ International Conference on Robotics and Intelligent Systems, IROS 2012
AU - Owaki, Hirofumi
AU - Masuda, Taisuke
AU - Kawahara, Tomohiro
AU - Takei, Natsuki
AU - Miwa-Kodama, Keiko
AU - Miyasaka, Kota
AU - Ogura, Toshihiko
AU - Arai, Fumihito
PY - 2012/12/1
Y1 - 2012/12/1
N2 - In this paper, we newly propose an organ-explanted bionic simulator (OBiS) using an isolated organ tissue. We use a heart isolated from the chick embryo for proposed simulator. To achieve the OBiS, we perform the concurrent microvascular anastomosis by using suction-induced vascular fixation (SVF) method for easily connection to artificial tubes with blood vessels led to the explanted chick's heart. Through the experiment with a simulated cardiovascular, it is confirmed that vessels can be aligned by using the proposed method. In addition, we have succeeded in connecting the Alg tubes with the blood vessels led to the heart of chick embryo. OBiS is available for the evaluation of new drugs immune response not only without using large animals but also as a response of organs beyond cellular level.
AB - In this paper, we newly propose an organ-explanted bionic simulator (OBiS) using an isolated organ tissue. We use a heart isolated from the chick embryo for proposed simulator. To achieve the OBiS, we perform the concurrent microvascular anastomosis by using suction-induced vascular fixation (SVF) method for easily connection to artificial tubes with blood vessels led to the explanted chick's heart. Through the experiment with a simulated cardiovascular, it is confirmed that vessels can be aligned by using the proposed method. In addition, we have succeeded in connecting the Alg tubes with the blood vessels led to the heart of chick embryo. OBiS is available for the evaluation of new drugs immune response not only without using large animals but also as a response of organs beyond cellular level.
UR - http://www.scopus.com/inward/record.url?scp=84872332665&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84872332665&partnerID=8YFLogxK
U2 - 10.1109/IROS.2012.6386209
DO - 10.1109/IROS.2012.6386209
M3 - Conference contribution
AN - SCOPUS:84872332665
SN - 9781467317375
T3 - IEEE International Conference on Intelligent Robots and Systems
SP - 3812
EP - 3817
BT - 2012 IEEE/RSJ International Conference on Intelligent Robots and Systems, IROS 2012
Y2 - 7 October 2012 through 12 October 2012
ER -